Pub. Date : 2000 Dec 18
PMID : 11137498
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Sildenafil is a potent and selective inhibitor of phosphodiesterase type 5 (PDE5), the enzyme responsible for the degradation of cyclic guanosine monophosphate (cGMP). | Sildenafil Citrate | phosphodiesterase 5A | Homo sapiens |
| 2 | Sildenafil is a potent and selective inhibitor of phosphodiesterase type 5 (PDE5), the enzyme responsible for the degradation of cyclic guanosine monophosphate (cGMP). | Sildenafil Citrate | phosphodiesterase 5A | Homo sapiens |
| 3 | Because PDE5 is also present in small amounts in the systemic vasculature, sildenafil can cause a synergistic and major decrease in pressure when combined with organic nitrates. | Sildenafil Citrate | phosphodiesterase 5A | Homo sapiens |