Pub. Date : 2001 Jan
PMID : 11124226
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Potent inhibitors of CYP1A2 were artemisinin, dihydroartemisinin, thiabendazole, primaquine, and niclosamide (K(i) = 0.43, 3.67, 1.54, 0.22, and 2.70 microM, respectively). | Thiabendazole | cytochrome P450 family 1 subfamily A member 2 | Homo sapiens |
| 2 | In addition, our results suggest CYP1A2 inhibition as the mechanism behind the observed thiabendazole/theophylline and primaquine/antipyrine interactions in vivo. | Thiabendazole | cytochrome P450 family 1 subfamily A member 2 | Homo sapiens |