Title : Membrane raft association of CD47 is necessary for actin polymerization and protein kinase C theta translocation in its synergistic activation of T cells.

Pub. Date : 2001 Mar 9

PMID : 11114301






1 Functional Relationships(s)
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1 Disruption of membrane rafts by removal of cholesterol with cyclodextrin blocked CD47-induced actin polymerization, and mutant forms of CD47 that localized poorly to rafts failed to effect cytoskeletal rearrangement. Cholesterol CD47 molecule Homo sapiens