Title : Release of plasminogen activator inhibitor-1 from human astrocytes is regulated by intracellular ceramide.

Pub. Date : 2000 Dec 15

PMID : 11107162






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Treatment of cultured human astrocytes with N-acetylsphingosine, a cell-permeable short-chain ceramide analogue or daunorubicin that could increase intracellular ceramide via activation of ceramide synthase or sphingomyelin hydrolysis increased the release of t-PA and conversely decreased the PAI-1 release. Daunorubicin plasminogen activator, tissue type Homo sapiens