Title : beta-adrenergic stimulation of rat cardiac fibroblasts enhances induction of nitric-oxide synthase by interleukin-1beta via message stabilization.

Pub. Date : 2000 Dec

PMID : 11093787






3 Functional Relationships(s)
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1 Nuclear run-off experiments indicate that enhancement of iNOS by isoproterenol does not occur at the level of transcription. Isoproterenol nitric oxide synthase 2 Rattus norvegicus
2 Message stability studies demonstrate that isoproterenol increases the half-life of iNOS mRNA from 1.0 to 1.9 h; this change is sufficient to account for the observed augmentation of iNOS mRNA and protein. Isoproterenol nitric oxide synthase 2 Rattus norvegicus
3 Message stability studies demonstrate that isoproterenol increases the half-life of iNOS mRNA from 1.0 to 1.9 h; this change is sufficient to account for the observed augmentation of iNOS mRNA and protein. Isoproterenol nitric oxide synthase 2 Rattus norvegicus