Title : Induction of p27(KIP1) as a mechanism underlying NS398-induced growth inhibition in human lung cancer cells.

Pub. Date : 2000 Dec

PMID : 11093779






1 Functional Relationships(s)
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1 We conclude that NS398 enhances p27(KIP1) expression via post-translational regulation, and our results provide a new mechanism by which specific COX-2 inhibitors suppress proliferation of cancer cells. N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide cyclin dependent kinase inhibitor 1B Homo sapiens