Title : Mitochondrial dysfunction increases expression of endothelin-1 and induces apoptosis through caspase-3 activation in rat cardiomyocytes in vitro.

Pub. Date : 2000 Nov

PMID : 11078378






1 Functional Relationships(s)
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1 Furthermore, treatment of cardiomyocytes with rotenone induced an elevation of caspase-3 activity, and caused a marked increase in DNA laddering, an indication of apoptosis. Rotenone caspase 3 Rattus norvegicus