Title : The inhibitory potency and selectivity of arginine substrate site nitric-oxide synthase inhibitors is solely determined by their affinity toward the different isoenzymes.

Pub. Date : 2000 Nov

PMID : 11040050






1 Functional Relationships(s)
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1 High iNOS versus eNOS selectivity was found for 1400W, whereas several isothiourea derivatives and 1400W displayed moderate n- versus eNOS selectivity. N-((3-(aminomethyl)phenyl)methyl)ethanimidamide nitric oxide synthase 3 Homo sapiens