Title : Decreased in vivo metabolism of drugs in chronic renal failure.

Pub. Date : 2000 Nov

PMID : 11038159






2 Functional Relationships(s)
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1 In vivo cytochrome P450 activity was evaluated with breath tests using substrates for different isoenzymes: caffeine (CYP1A2), aminopyrine (CYP2C11), and erythromycin (CYP3A2). Caffeine cytochrome P450, family 1, subfamily a, polypeptide 2 Rattus norvegicus
2 The caffeine (CYP1A2) breath tests remained comparable to controls. Caffeine cytochrome P450, family 1, subfamily a, polypeptide 2 Rattus norvegicus