Title : A simple phenolic antioxidant protocatechuic acid enhances tumor promotion and oxidative stress in female ICR mouse skin: dose-and timing-dependent enhancement and involvement of bioactivation by tyrosinase.

Pub. Date : 2000 Oct

PMID : 11023549






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Treatment with a high dose (20000 nmol) of PA alone for 3h enhanced oxidative stress by reducing glutathione levels in mouse skin, which was counteracted by the tyrosinase inhibitor arbutin. Arbutin tyrosinase Mus musculus