Title : Specific activation of LIM kinase 2 via phosphorylation of threonine 505 by ROCK, a Rho-dependent protein kinase.

Pub. Date : 2001 Jan 5

PMID : 11018042






1 Functional Relationships(s)
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1 These results indicate that ROCK directly phosphorylates threonine 505 and activates LIMK2 downstream of RhoA and that this phosphorylation is essential for LIMK2 to induce actin cytoskeletal reorganization. Threonine ras homolog family member A Homo sapiens