Title : Validation of bupropion hydroxylation as a selective marker of human cytochrome P450 2B6 catalytic activity.

Pub. Date : 2000 Oct

PMID : 10997944






1 Functional Relationships(s)
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1 Among a panel of cDNA-expressed P450 isoforms, CYP2B6 and CYP2E1 demonstrated the highest rates of BUP hydroxylation at 12 mM BUP (7.0 and 2.4 pmol/min/pmol of P450, respectively). Bupropion cytochrome P450 family 2 subfamily E member 1 Homo sapiens