Title : Binding of aminoacyl-tRNA to ribosomes promoted by elongation factor Tu. Studies on the role of GTP hydrolysis.

Pub. Date : 1975 Apr

PMID : 1097432






12 Functional Relationships(s)
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1 The role of guanosine triphosphate (GTP) in the elongation factor Tu(EF-Tu)promoted binding of aminoacyl-tRNA to ribosomes has been investigated. Guanosine Triphosphate eukaryotic translation elongation factor 1 alpha 1 Homo sapiens
2 The role of guanosine triphosphate (GTP) in the elongation factor Tu(EF-Tu)promoted binding of aminoacyl-tRNA to ribosomes has been investigated. Guanosine Triphosphate eukaryotic translation elongation factor 1 alpha 1 Homo sapiens
3 The role of guanosine triphosphate (GTP) in the elongation factor Tu(EF-Tu)promoted binding of aminoacyl-tRNA to ribosomes has been investigated. Guanosine Triphosphate eukaryotic translation elongation factor 1 alpha 1 Homo sapiens
4 The role of guanosine triphosphate (GTP) in the elongation factor Tu(EF-Tu)promoted binding of aminoacyl-tRNA to ribosomes has been investigated. Guanosine Triphosphate eukaryotic translation elongation factor 1 alpha 1 Homo sapiens
5 It was concluded that the role of GTP in this reaction is to facilitate the transfer of Phe-tRNA to ribosomes by virtue of the high affinity of EF-Tu.GTP for ribosomes. Guanosine Triphosphate eukaryotic translation elongation factor 1 alpha 1 Homo sapiens
6 It was concluded that the role of GTP in this reaction is to facilitate the transfer of Phe-tRNA to ribosomes by virtue of the high affinity of EF-Tu.GTP for ribosomes. Guanosine Triphosphate eukaryotic translation elongation factor 1 alpha 1 Homo sapiens
7 The subsequent conversion of EF-Tu.GTP to EF-Tu.GDP, a form of EF-Tu with low affinity for ribosomes as well as for Phe-tRNA, resulted in the detachment of EF-Tu. Guanosine Triphosphate eukaryotic translation elongation factor 1 alpha 1 Homo sapiens
8 The subsequent conversion of EF-Tu.GTP to EF-Tu.GDP, a form of EF-Tu with low affinity for ribosomes as well as for Phe-tRNA, resulted in the detachment of EF-Tu. Guanosine Triphosphate eukaryotic translation elongation factor 1 alpha 1 Homo sapiens
9 The subsequent conversion of EF-Tu.GTP to EF-Tu.GDP, a form of EF-Tu with low affinity for ribosomes as well as for Phe-tRNA, resulted in the detachment of EF-Tu. Guanosine Triphosphate eukaryotic translation elongation factor 1 alpha 1 Homo sapiens
10 The subsequent conversion of EF-Tu.GTP to EF-Tu.GDP, a form of EF-Tu with low affinity for ribosomes as well as for Phe-tRNA, resulted in the detachment of EF-Tu. Guanosine Triphosphate eukaryotic translation elongation factor 1 alpha 1 Homo sapiens
11 Thus, the hydrolysis of GTP seems to be required for the release of EF-Tu from ribosomes, which is necessary for peptidyl transfer and the reutilization of EF-Tu. Guanosine Triphosphate eukaryotic translation elongation factor 1 alpha 1 Homo sapiens
12 Thus, the hydrolysis of GTP seems to be required for the release of EF-Tu from ribosomes, which is necessary for peptidyl transfer and the reutilization of EF-Tu. Guanosine Triphosphate eukaryotic translation elongation factor 1 alpha 1 Homo sapiens