Title : Differential antiplatelet efficacy for various GPIIb/IIIa antagonists: role of plasma calcium levels.

Pub. Date : 2000 Sep

PMID : 10974231






1 Functional Relationships(s)
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1 RESULTS: A significantly higher IC50s was shown with heparin (free ionized calcium=1.1 mM) as compared to that with citrate (free ionized calcium=0.12 mM) with class II GPIIb/IIIa antagonists (P<0.01) such as Orbofiban, and Integrilin. Heparin integrin subunit alpha 2b Homo sapiens