Title : Anti-apoptotic effect of quercetin: intervention in the JNK- and ERK-mediated apoptotic pathways.

Pub. Date : 2000 Sep

PMID : 10972672






1 Functional Relationships(s)
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1 CONCLUSIONS: These results suggested that (1) activation of JNK and ERKs, but not p38 kinase, is required for the H2O2-induced apoptosis; and (2) suppression of the JNK-c-Jun/AP-1 pathway and the ERK-c-Fos/AP-1 pathway is involved in the anti-apoptotic effect of quercetin. Quercetin mitogen-activated protein kinase 3 Homo sapiens