Pub. Date : 2000 Sep 1
PMID : 10961875
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The importance of MAPK and Akt/PKB signaling pathways in regulating the expression of Mcl-1 and cell survival was further supported by the observation that inhibition of MEK by PD98059 or phosphatidylinositol-3 kinase (PI-3K) by LY294002 independently resulted in the reduction of Mcl-1 expression and loss of cell viability. | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | MCL1 apoptosis regulator, BCL2 family member | Homo sapiens |