Title : Permeability barrier disorder in Niemann-Pick disease: sphingomyelin-ceramide processing required for normal barrier homeostasis.

Pub. Date : 2000 Sep

PMID : 10951284






1 Functional Relationships(s)
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1 Furthermore, both palmitoyldihydrosphingosine and desipramine, a chemically and mechanically unrelated acid-sphingomyelinase inhibitor, significantly delay barrier recovery both 2 and 4 h after acute barrier abrogation. Desipramine sphingomyelin phosphodiesterase 1 Homo sapiens