Pub. Date : 2000 Jul
PMID : 10947823
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | This nicotinic response was almost completely absent in beta2-/- mutant mice, leaving a small residual response to a high concentration (100 microM) of nicotine which was inhibited by the alpha7-subunit-selective antagonist, methyllycaconitine. | Nicotine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |
| 2 | These results demonstrate that in nigral dopaminergic neurons, nicotine can elicit Ca2+ mobilization via activation of two distinct nAChR subtypes: that of beta2-subunit-containing nAChR followed by activation of Na+ channel and T-type Ca2+ channels, and/or activation of alpha7-subunit-containing nAChR. | Nicotine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |
| 3 | These results demonstrate that in nigral dopaminergic neurons, nicotine can elicit Ca2+ mobilization via activation of two distinct nAChR subtypes: that of beta2-subunit-containing nAChR followed by activation of Na+ channel and T-type Ca2+ channels, and/or activation of alpha7-subunit-containing nAChR. | Nicotine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |
| 4 | These results demonstrate that in nigral dopaminergic neurons, nicotine can elicit Ca2+ mobilization via activation of two distinct nAChR subtypes: that of beta2-subunit-containing nAChR followed by activation of Na+ channel and T-type Ca2+ channels, and/or activation of alpha7-subunit-containing nAChR. | Nicotine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |
| 5 | These results demonstrate that in nigral dopaminergic neurons, nicotine can elicit Ca2+ mobilization via activation of two distinct nAChR subtypes: that of beta2-subunit-containing nAChR followed by activation of Na+ channel and T-type Ca2+ channels, and/or activation of alpha7-subunit-containing nAChR. | Nicotine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |