Title : Partial agonism through a zinc-Ion switch constructed between transmembrane domains III and VII in the tachykinin NK(1) receptor.

Pub. Date : 2000 Aug

PMID : 10908293






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The metal-ion chelator, phenantroline, which in the beta(2)-adrenergic receptor increased both the potency and the agonistic efficacy of Zn(2+) or Cu(2+) in complex with the chelator, also bound to the metal-ion site-engineered NK(1) receptor, but here the metal-ion chelator complex instead acted as a pure antagonist. 1,10-phenanthroline adrenoceptor beta 2 Homo sapiens