Title : Biotin reagents for antibody pretargeting. 4. Selection of biotin conjugates for in vivo application based on their dissociation rate from avidin and streptavidin.

Pub. Date : 2000 Jul-Aug

PMID : 10898580






3 Functional Relationships(s)
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1 Two biotin-CN-Cbl conjugates, one containing unaltered biotin and the other containing iminobiotin, were prepared as reference compounds for comparison purposes. Biotin Cbl proto-oncogene Homo sapiens
2 The rate of dissociation of the biotin-CN-Cbl derivative from Av and SAv was significantly increased for biotin derivatives containing those structural features. Biotin Cbl proto-oncogene Homo sapiens
3 The rate of dissociation of the biotin-CN-Cbl derivative from Av and SAv was significantly increased for biotin derivatives containing those structural features. Biotin Cbl proto-oncogene Homo sapiens