Title : Generation of alphabeta T-cell receptor+ CD4- CD8+ cells in major histocompatibility complex class I-deficient mice upon activation of the aryl hydrocarbon receptor by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Pub. Date : 2000 Jun

PMID : 10886394






2 Functional Relationships(s)
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1 When beta2m-/- dams were given a single dose of 50 microg of TCDD, approximately 13% of CD4- CD8+ thymocytes could be detected in their newborn pups. Polychlorinated Dibenzodioxins beta-2 microglobulin Mus musculus
2 In TCDD-exposed fetal thymus organ cultures of beta2m-/- mice, approximately 35% CD4- CD8+ thymocytes were detectable. Polychlorinated Dibenzodioxins beta-2 microglobulin Mus musculus