Title : Hypothalamic dopaminergic tone and prolactin bioactivity in women with polycystic ovary syndrome.

Pub. Date : 2000 Mar-Apr

PMID : 10880731






2 Functional Relationships(s)
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1 METHODS: Our group evaluated the response of pituitary PRL, LH, FSH, and TSH to the administration of a single 10-mg oral dose of the dopamine (DA) receptor antagonist metoclopramide in lean (n = 7) and obese (n = 8) PCOS women and in 11 regularly cycling age- and weight-matched controls (six lean and five obese). Metoclopramide prolactin Homo sapiens
2 RESULTS: Oral administration of metoclopramide resulted in a significant increase in serum PRL in all subjects; however, the highest increments, regardless of body mass index (BMI), were observed in control women (p <0.005). Metoclopramide prolactin Homo sapiens