Pub. Date : 2000 Jun
PMID : 10875492
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Interleukin-8 in the sputa from GD-induced asthmatic patients increased significantly after the exposure to GD. | Gadolinium | C-X-C motif chemokine ligand 8 | Homo sapiens |
| 2 | Interleukin-8 in the sputa from GD-induced asthmatic patients increased significantly after the exposure to GD. | Gadolinium | C-X-C motif chemokine ligand 8 | Homo sapiens |
| 3 | OBJECTIVE: To confirm IL-8 production from bronchial epithelial cells when exposed to GD, and to evaluate the role of IL-8 on neutrophil recruitment. | Gadolinium | C-X-C motif chemokine ligand 8 | Homo sapiens |
| 4 | RESULTS: Interleukin-8 production and neutrophil chemotactic activity from bronchial epithelial cells significantly increased with additions of GD in a dose-dependent manner (P < .05, respectively), and were significantly augmented with additions of PBMC supernatant (P < .05, respectively) at each concentration. | Gadolinium | C-X-C motif chemokine ligand 8 | Homo sapiens |
| 5 | CONCLUSION: These results suggest that IL-8 produced from bronchial epithelial cells may be a major cytokine, which induces neutrophil migration into the airways when exposed to GD. | Gadolinium | C-X-C motif chemokine ligand 8 | Homo sapiens |