PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10875492-2 2000 Interleukin-8 in the sputa from GD-induced asthmatic patients increased significantly after the exposure to GD. Gadolinium 32-34 C-X-C motif chemokine ligand 8 Homo sapiens 0-13 10875492-2 2000 Interleukin-8 in the sputa from GD-induced asthmatic patients increased significantly after the exposure to GD. Gadolinium 108-110 C-X-C motif chemokine ligand 8 Homo sapiens 0-13 10875492-3 2000 OBJECTIVE: To confirm IL-8 production from bronchial epithelial cells when exposed to GD, and to evaluate the role of IL-8 on neutrophil recruitment. Gadolinium 86-88 C-X-C motif chemokine ligand 8 Homo sapiens 22-26 10875492-9 2000 RESULTS: Interleukin-8 production and neutrophil chemotactic activity from bronchial epithelial cells significantly increased with additions of GD in a dose-dependent manner (P < .05, respectively), and were significantly augmented with additions of PBMC supernatant (P < .05, respectively) at each concentration. Gadolinium 144-146 C-X-C motif chemokine ligand 8 Homo sapiens 9-22 10875492-12 2000 CONCLUSION: These results suggest that IL-8 produced from bronchial epithelial cells may be a major cytokine, which induces neutrophil migration into the airways when exposed to GD. Gadolinium 178-180 C-X-C motif chemokine ligand 8 Homo sapiens 39-43