Title : Cure of refractory duodenal ulcer and infection caused by Helicobacter pylori by high doses of omeprazole and amoxicillin in a homozygous CYP2C19 extensive metabolizer patient.

Pub. Date : 2000 Jun

PMID : 10872651






2 Functional Relationships(s)
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1 Cure of refractory duodenal ulcer and infection caused by Helicobacter pylori by high doses of omeprazole and amoxicillin in a homozygous CYP2C19 extensive metabolizer patient. Amoxicillin cytochrome P450 family 2 subfamily C member 19 Homo sapiens
2 Dual treatment with a sufficient dose of a proton pump inhibitor plus amoxicillin could cure H pylori infection even after the failure to cure H pylori infection by a usual proton pump inhibitor-based triple therapy in patients with the wt/wt homozygous extensive metabolizer genotype of CYP2C19. Amoxicillin cytochrome P450 family 2 subfamily C member 19 Homo sapiens