Title : Celecoxib does not significantly alter the pharmacokinetics or hypoprothrombinemic effect of warfarin in healthy subjects.

Pub. Date : 2000 Jun

PMID : 10868317






1 Functional Relationships(s)
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1 The objective of this study was to determine the effects of celecoxib, an anti-inflammatory/analgesic agent that primarily inhibits COX-2 and not COX-1 at therapeutic doses, on the steady-state pharmacokinetic profile and hypoprothrombinemic effect of racemic warfarin in healthy volunteers. Celecoxib mitochondrially encoded cytochrome c oxidase I Homo sapiens