Title : Regulation of the MDR1 gene by transcriptional repressors selected using peptide combinatorial libraries.

Pub. Date : 2000 Jul

PMID : 10860921






3 Functional Relationships(s)
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1 Thus, in K562 cells, 12-O-tetradecanoylphorbol-13-acetate-inducible expression of P-glycoprotein, the product of MDR1 gene, was strongly and selectively inhibited by the presence of a repressor protein targeted to the MDR1 promoter. Tetradecanoylphorbol Acetate ATP binding cassette subfamily B member 1 Homo sapiens
2 Thus, in K562 cells, 12-O-tetradecanoylphorbol-13-acetate-inducible expression of P-glycoprotein, the product of MDR1 gene, was strongly and selectively inhibited by the presence of a repressor protein targeted to the MDR1 promoter. Tetradecanoylphorbol Acetate ATP binding cassette subfamily B member 1 Homo sapiens
3 Thus, in K562 cells, 12-O-tetradecanoylphorbol-13-acetate-inducible expression of P-glycoprotein, the product of MDR1 gene, was strongly and selectively inhibited by the presence of a repressor protein targeted to the MDR1 promoter. Tetradecanoylphorbol Acetate ATP binding cassette subfamily B member 1 Homo sapiens