Title : Novel role for the nuclear phosphoprotein SET in transcriptional activation of P450c17 and initiation of neurosteroidogenesis.

Pub. Date : 2000 Jun

PMID : 10847589






3 Functional Relationships(s)
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1 The crucial enzyme for the synthesis of DHEA (dehydroepiandrosterone) in the brain is cytochrome P450c17. Dehydroepiandrosterone cytochrome P450 family 17 subfamily A member 1 Homo sapiens
2 The crucial enzyme for the synthesis of DHEA (dehydroepiandrosterone) in the brain is cytochrome P450c17. Dehydroepiandrosterone cytochrome P450 family 17 subfamily A member 1 Homo sapiens
3 These studies delineate an important new factor in the transcriptional regulation of P450c17 and consequently, in the production of DHEA and sex steroids. Dehydroepiandrosterone cytochrome P450 family 17 subfamily A member 1 Homo sapiens