Title : Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130.

Pub. Date : 2000 Jun 6

PMID : 10829066






1 Functional Relationships(s)
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1 The only high-affinity ligand found corresponded to the region of gp130 centered around phosphotyrosine-757 (pY757), previously shown to be a docking site for the tyrosine phosphatase SHP-2. Phosphotyrosine protein tyrosine phosphatase non-receptor type 11 Homo sapiens