Title : Effects of aspirin-like drugs on nitric oxide synthesis in rat vascular smooth muscle cells.

Pub. Date : 2000 May

PMID : 10818069






3 Functional Relationships(s)
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1 Increased nitrite production by aspirin-like drugs was accompanied by increased iNOS mRNA and protein accumulation in VSMCs. Aspirin nitric oxide synthase 2 Rattus norvegicus
2 Our study demonstrates that aspirin and the aspirin-like drugs, sodium salicylate and indomethacin, increase NO synthesis in IL-1beta-stimulated VSMCs by upregulation of iNOS transcription via a 12-LO pathway. Aspirin nitric oxide synthase 2 Rattus norvegicus
3 Our study demonstrates that aspirin and the aspirin-like drugs, sodium salicylate and indomethacin, increase NO synthesis in IL-1beta-stimulated VSMCs by upregulation of iNOS transcription via a 12-LO pathway. Aspirin nitric oxide synthase 2 Rattus norvegicus