Title : Bcl-2 phosphorylation in a human breast carcinoma xenograft: a common event in response to effective DNA-damaging drugs.

Pub. Date : 2000 Jul 1

PMID : 10807947






1 Functional Relationships(s)
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1 A comparison of effects of drugs belonging to the same class but endowed with a different antitumor activity (i.e. cisplatin versus a novel multinuclear platinum complex and doxorubicin versus a disaccharide analogue) showed a correlation between drug efficacy, apoptotic response, and Bcl-2 phosphorylation. Cisplatin BCL2 apoptosis regulator Homo sapiens