Title : Protein-tyrosine phosphatase reduces the number of apical small conductance K+ channels in the rat cortical collecting duct.

Pub. Date : 2000 Jul 7

PMID : 10787405






3 Functional Relationships(s)
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1 Application of 1 microm phenylarsine oxide (PAO) or 1 mm benzylphosphonic acid, agents that inhibit PTP, reversibly reduced channel activity by 95%. oxophenylarsine protein tyrosine phosphatase, non-receptor type 1 Rattus norvegicus
2 Application of 1 microm phenylarsine oxide (PAO) or 1 mm benzylphosphonic acid, agents that inhibit PTP, reversibly reduced channel activity by 95%. oxophenylarsine protein tyrosine phosphatase, non-receptor type 1 Rattus norvegicus
3 However, herbimycin A abolished the inhibitory effect of PAO, indicating that the effect of PAO is the result of interaction between PTK and PTP. oxophenylarsine protein tyrosine phosphatase, non-receptor type 1 Rattus norvegicus