Title : The inhibition of ERK/MAPK not the activation of JNK/SAPK is primarily required to induce apoptosis in chronic myelogenous leukemic K562 cells.

Pub. Date : 2000 Jun

PMID : 10781688






3 Functional Relationships(s)
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1 During the apoptosis induced by the treatment of herbimycin A, stress-activated protein kinase (SAPK) and p38 kinase were activated time- and dose-dependently, while extracellular signal-regulated kinase (ERK) was inhibited. herbimycin mitogen-activated protein kinase 1 Homo sapiens
2 During the apoptosis induced by the treatment of herbimycin A, stress-activated protein kinase (SAPK) and p38 kinase were activated time- and dose-dependently, while extracellular signal-regulated kinase (ERK) was inhibited. herbimycin mitogen-activated protein kinase 1 Homo sapiens
3 During the apoptosis induced by the treatment of herbimycin A, stress-activated protein kinase (SAPK) and p38 kinase were activated time- and dose-dependently, while extracellular signal-regulated kinase (ERK) was inhibited. herbimycin mitogen-activated protein kinase 1 Homo sapiens