Title : The guanine nucleotide exchange factor RasGRP is a high -affinity target for diacylglycerol and phorbol esters.

Pub. Date : 2000 May

PMID : 10779365






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The phorbol ester [(3)H]phorbol 12, 13-dibutyrate ([(3)H]PDBu) bound to this C1 domain (C1-RasGRP) with a dissociation constant of 0.58 +/- 0.08 nM, similar to that observed previously for PKC. Tritium RAS guanyl releasing protein 1 Homo sapiens