Title : Detection of chemical-induced differential expression of rat hepatic cytochrome P450 mRNA transcripts using branched DNA signal amplification technology.

Pub. Date : 2000 May

PMID : 10772642






1 Functional Relationships(s)
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1 Male Sprague-Dawley rats were administered 3-methylcholanthrene, PB, isoniazid, pregnenolone-16alpha-carbonitrile, or clofibric acid to induce transcription of CYP1A1, CYP1A2, CYP2B1/2, CYP2E1, CYP3A1/23, and CYP4A2/3 mRNA, respectively. Pregnenolone Carbonitrile cytochrome P450, family 1, subfamily a, polypeptide 1 Rattus norvegicus