Title : Activation of the cytoplasmic c-Abl tyrosine kinase by reactive oxygen species.

Pub. Date : 2000 Jun 9

PMID : 10770918






2 Functional Relationships(s)
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1 The results also demonstrate that mitochondrial cytochrome c is released in the cellular response to H(2)O(2) and that this effect is mediated by a c-Abl-dependent mechanism. Hydrogen Peroxide ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens
2 In concert with these results, we show that H(2)O(2)-induced apoptosis is attenuated in c-Abl-deficient cells. Hydrogen Peroxide ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens