Title : Inositol stereoisomers stabilize an oligomeric aggregate of Alzheimer amyloid beta peptide and inhibit abeta -induced toxicity.

Pub. Date : 2000 Jun 16

PMID : 10764800






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The attenuation of toxicity is the result of Abeta-inositol interaction, as inositol uptake inhibitors had no effect on neuronal survival. Inositol amyloid beta precursor protein Homo sapiens
2 Inositol stereoisomers are naturally occurring molecules that readily cross the blood-brain barrier and may represent a viable treatment for AD through the complexation of Abeta and attenuation of Abeta neurotoxic effects. Inositol amyloid beta precursor protein Homo sapiens