Title : Low-level doxorubicin resistance in benzo[a]pyrene-treated KB-3-1 cells is associated with increased LRP expression and altered subcellular drug distribution.

Pub. Date : 2000 Apr 15

PMID : 10764626






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The P-glycoprotein (P-gp)-negative epidermoid pharyngeal carcinoma cells KB-3-1 were grown in 0.25 mM benzo[a]pyrene (BaP) for 3 months and increased resistance to doxorubicin, but not to vinblastine, colchicine, or cisplatin, was found. Cisplatin ATP binding cassette subfamily B member 1 Homo sapiens