Title : Cyclin-dependent kinase inhibition by new C-2 alkynylated purine derivatives and molecular structure of a CDK2-inhibitor complex.

Pub. Date : 2000 Apr 6

PMID : 10753466






1 Functional Relationships(s)
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1 The structure of compound 4b (N-6-p-methoxybenzylamino derivative) in complex with human CDK2 was determined by X-ray crystallography, revealing the molecular basis of inhibition by this molecule. n-6-p-methoxybenzylamino cyclin dependent kinase 2 Homo sapiens