Pub. Date : 2000 Mar
PMID : 10749518
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Celecoxib is metabolised primarily by the cytochrome P450 (CYP) 2C9 isoenzyme and has an elimination half-life of about 11 hours in healthy individuals. | Celecoxib | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |
| 2 | As celecoxib is metabolised by CYP2C9, increased clinical vigilance is required during the coadministration of other substrates or inhibitors of this enzyme. | Celecoxib | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |