Title : Disruption of the oxysterol 7alpha-hydroxylase gene in mice.

Pub. Date : 2000 Jun 2

PMID : 10748048






1 Functional Relationships(s)
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1 Plasma and tissue levels of 25- and 27-hydroxycholesterol, two oxysterol substrates of this enzyme with potent regulatory actions in cultured cells, were markedly elevated in Cyp7b1(-/-) knockout animals. Oxysterols cytochrome P450, family 7, subfamily b, polypeptide 1 Mus musculus