Title : NF-kappaB activation by camptothecin. A linkage between nuclear DNA damage and cytoplasmic signaling events.

Pub. Date : 2000 Mar 31

PMID : 10734098






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 NF-kappaB activation by camptothecin. Camptothecin nuclear factor kappa B subunit 1 Homo sapiens
2 NF-kappaB can also be activated by the anticancer agent camptothecin (CPT), which inhibits DNA topoisomerase (Topo) I activity and causes DNA double-strand breaks during DNA replication to induce S phase-dependent cytotoxicity. Camptothecin nuclear factor kappa B subunit 1 Homo sapiens
3 NF-kappaB can also be activated by the anticancer agent camptothecin (CPT), which inhibits DNA topoisomerase (Topo) I activity and causes DNA double-strand breaks during DNA replication to induce S phase-dependent cytotoxicity. Camptothecin nuclear factor kappa B subunit 1 Homo sapiens