Pub. Date : 1999
PMID : 10731095
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | IDO is a unique enzyme in that it can utilize superoxide anion radical (O2*- ) as both a substrate and a co-factor. | Superoxides | indoleamine 2,3-dioxygenase 1 | Homo sapiens |
| 2 | IDO is a unique enzyme in that it can utilize superoxide anion radical (O2*- ) as both a substrate and a co-factor. | Superoxides | indoleamine 2,3-dioxygenase 1 | Homo sapiens |
| 3 | The latter role is due to the ability of O2*- to reduce inactive ferric-IDO to the active ferrous form. | Superoxides | indoleamine 2,3-dioxygenase 1 | Homo sapiens |
| 4 | Antioxidant activity may arise from O2*- scavenging by IDO and formation of the potent radical scavengers and Kyn pathway metabolites, 3-hydroxyanthranilic acid and 3-hydroxykynurenine. | Superoxides | indoleamine 2,3-dioxygenase 1 | Homo sapiens |