Title : Inhibition of the P-glycoprotein- and multidrug resistance protein-mediated efflux of anthracyclines and calceinacetoxymethyl ester by PAK-104P.

Pub. Date : 2000 Mar 17

PMID : 10729360






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We now examined the effect of PAK-104P on Pgp-and MRP1-mediated efflux of three anthracyclines, daunorubicin, pirarubicin, hydroxydoxorubicin and of calcein acetoxymethyl ester and calcein. Daunorubicin ATP binding cassette subfamily C member 1 Homo sapiens
2 PAK-104P also non-competitively inhibits the MRP(1)-mediated efflux of daunorubicin, pirarubicin, hydroxyrubicin, calcein acetoxymethyl ester and calcein. Daunorubicin ATP binding cassette subfamily C member 1 Homo sapiens