Title : Differential impact of nicotine on cellular proliferation and cytokine production by LPS-stimulated murine splenocytes.

Pub. Date : 2000 Jun

PMID : 10727751






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 TNF-alpha and IL-6 production were significantly enhanced by 1 microg/ml of nicotine when cells were pre-incubated with nicotine for 3 h compared to concurrent incubation relative to LPS stimulation. Nicotine tumor necrosis factor Mus musculus
2 TNF-alpha and IL-6 production were significantly enhanced by 1 microg/ml of nicotine when cells were pre-incubated with nicotine for 3 h compared to concurrent incubation relative to LPS stimulation. Nicotine tumor necrosis factor Mus musculus
3 TNF-alpha production was significantly inhibited by nicotine in young mice, while IL-6 production was significantly inhibited by nicotine in old mice. Nicotine tumor necrosis factor Mus musculus