Title : Molecular cloning and characterization of a distinct human phosphodiesterase gene family: PDE11A.

Pub. Date : 2000 Mar 28

PMID : 10725373






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 PDE11A is sensitive to the nonselective PDE inhibitor 3-isobutyl-1-methylxanthine (IBMX) as well as zaprinast and dipyridamole, inhibitors that are generally considered relatively specific for the cGMP-selective PDEs, with IC(50) values of 49.8 microM, 12.0 microM, and 0.37 microM, respectively. Dipyridamole phosphodiesterase 11A Homo sapiens
2 PDE11A is sensitive to the nonselective PDE inhibitor 3-isobutyl-1-methylxanthine (IBMX) as well as zaprinast and dipyridamole, inhibitors that are generally considered relatively specific for the cGMP-selective PDEs, with IC(50) values of 49.8 microM, 12.0 microM, and 0.37 microM, respectively. Dipyridamole phosphodiesterase 11A Homo sapiens