Title : Fusion of beta 2-adrenergic receptor to G alpha s in mammalian cells: identification of a specific signal transduction species not characteristic of constitutive activation or precoupling.

Pub. Date : 2000 Mar 14

PMID : 10704234






1 Functional Relationships(s)
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1 Taken together, these results indicate that the tethering of G(alpha)(s) to the beta(2)AR causes a conformational change in the receptor that stabilizes a species "trapped" between the non-guanine nucleotide-bound state and the GTP-bound form. Guanosine Triphosphate adrenoceptor beta 2 Homo sapiens