Title : Ras signaling through PI3K confers hormone-independent proliferation that is compatible with differentiation.

Pub. Date : 2000 Feb 17

PMID : 10702801






1 Functional Relationships(s)
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1 Unlike the inhibitory effects of TSH on the proliferation of RasV12S35-expressing cells, TSH enhanced RasV12C40-stimulated proliferation by further increasing the activity of p70s6k, an important mediator of the mitogenic effects of TSH and RasV12C40. Thyrotropin ribosomal protein S6 kinase B1 Homo sapiens