Pub. Date : 2000 Feb 28
PMID : 10700573
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Sodium valproate inhibits production of TNF-alpha and IL-6 and activation of NF-kappaB. | Valproic Acid | interleukin 6 | Homo sapiens |
| 2 | VPA significantly inhibited LPS-induced production of TNF-alpha and IL-6 by THP-1 cells, whereas other AEDs did not. | Valproic Acid | interleukin 6 | Homo sapiens |
| 3 | The findings are consistent with the idea that VPA suppresses TNF-alpha and IL-6 production via inhibition of NF-kappaB activation. | Valproic Acid | interleukin 6 | Homo sapiens |