Title : 3,4-Methylenedioxymetamphetamine (ecstasy) induces c-fos-like protein and mRNA in rat organotypic dorsal striatal slices.

Pub. Date : 2000 Apr

PMID : 10700028






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1 3,4-Methylenedioxymetamphetamine (ecstasy) induces c-fos-like protein and mRNA in rat organotypic dorsal striatal slices. N-Methyl-3,4-methylenedioxyamphetamine Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
2 3,4-Methylenedioxymetamphetamine (ecstasy) induces c-fos-like protein and mRNA in rat organotypic dorsal striatal slices. N-Methyl-3,4-methylenedioxyamphetamine Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
3 In this study the effects of MDMA on the expression of c-fos mRNA by in situ hybridization as well as the c-fos-like protein by immunohistochemistry in isolated dorsal striatum was investigated. N-Methyl-3,4-methylenedioxyamphetamine Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
4 It was shown that 100 microM MDMA induced c-fos mRNA expression 30 min after treatment. N-Methyl-3,4-methylenedioxyamphetamine Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
5 We conclude that MDMA treatment leads to the induction of c-fos expression in isolated rat striatal slices. N-Methyl-3,4-methylenedioxyamphetamine Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus